EXPERIMENTAL SUBSTANTIATION OF THE POSSIBILITY OF INJECTING A GEL SUBSTANCE INTO LUNG TISSUE TO ACHIEVE AEROSTASIS
Keywords:
experimental studies; failure of aero- and hemostasis; Hemoben; with intraparenchymal administration; to achieve aerostasis;Abstract
Currently, substances used in clinical practice for local strengthening of the damaged lung area are often characterized by insufficient effectiveness and unidirectional effects. Taking into account the new method of using the implant to eliminate the failure of aero- and hemostasis, which had not been previously performed, the possibility of using the hemostatic drug Hemoben in the form of a gel for injection into lung tissue was initially studied. Toxicological studies have revealed that 3.3% Hemoben gel injected into the lung parenchyma at a dose of 1 ml per 1 g does not have an irritating and toxic effect. Thus, the proposed technique is characterized by the effectiveness and safety of its use, and the results obtained make it possible to apply this method in clinical practice.
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