ALLERGIK OFTALMOPATOLOGIYALARDA OLOPATADIN GIDROXLORID 0.1% TARKIBLI KO’Z TOMCHISINI SAMARADORLIGINI BAHOLASH
Keywords:
allergik oftalmopatologiyalar, semiz hujayra, olopatadin gidroxloridAbstract
Butun jahon sog’liqni saqlash tashkiloti (BJSST) tomonidan oxirgi 10 yil davomida o’tkazilgan epidemiologik tadqiqotlar statistik xulosasi, allergik kasalliklar chastotasining global o'sishini qayd etdi [1,7,13]. Jahon allergiya tashkiloti (JAT)ning rasmiy bayonotiga ko’ra, hozirda umumiy allergozlar miqdori 3 barobar, xususan allergik oftalmopatologiyalar uchrashi 25% gacha ko’paygan [2,4]. Allergik ko'z kasalliklarining immunopatogenetik asosini gistamin (H) retseptorlari faollashishi va semiz hujayralarning degranulyatsiyasi tashkil qiladi [5,9,12]. Ushbu maqolaning asosiy maqsadi – oftalmologiya amaliyotida nisbatan yangi topikal antiallergik preparat - olopatadin gidroxlorid (Olopatadin 0.1% ko'z tomchisi) bo'yicha mavjud ilmiy adabiyotlarni ko'rib chiqish va tahlil qilish, shuningdek, klinik tadqiqot orqali Olopatadin 0.1% eritmasi preparatining samaradorligini baholash.
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