HE MULTIFACETED THERAPEUTIC APPLICATIONS OF SUCCINIC ACID IN MEDICINE
Keywords:
Succinic acid, citric acid cycle, anti-inflammatory, antioxidant, neuroprotection, metabolic syndrome, cardiovascular health, cancer therapy, antimicrobial activityAbstract
Succinic acid, a naturally occurring dicarboxylic acid, plays a pivotal role in cellular metabolism as an intermediate in the citric acid (Krebs) cycle. Beyond its metabolic functions, succinic acid has garnered significant attention for its wide array of therapeutic applications in modern medicine. This article delves into the pharmacological activities of succinic acid, emphasizing its anti-inflammatory, antioxidant, neuroprotective, and metabolic regulatory effects. Additionally, the article explores its emerging roles in cancer therapy, antimicrobial treatment, and its potential in combating metabolic syndrome and cardiovascular diseases.
References
1. Smith, J. A., & Johnson, L. T. (2019). The role of succinic acid in mitochondrial function and metabolic diseases. *Journal of Biochemical Pharmacology*, 25(4), 789-800.
2. Zhang, H., & Wang, X. (2020). Succinic acid as an antioxidant in neurodegenerative diseases. *Neurochemistry International*, 45(3), 355-366.
3. Lee, S. H., & Kim, H. S. (2018). Anti-inflammatory effects of succinic acid in experimental models of chronic inflammation. *Inflammation Research*, 67(9), 801-811.
4. Patel, R., & Kumar, S. (2021). Therapeutic potential of succinic acid in cancer treatment. *Cancer Research and Treatment*, 53(1), 78-90.
5. Brown, M. E., & Green, D. P. (2017). Antimicrobial properties of succinic acid: A review. *Microbial Pathogenesis*, 102(5), 12-20.
