Metabolic Syndrome and Cardiovascular Risk in Women With Polycystic Ovary Syndrome: An Integrative Review of Mechanisms, Clinical Evidence, Real-World Data and Precision Prevention
Keywords:
polycystic ovary syndrome; metabolic syndrome; cardiovascular disease; insulin resistance; hyperandrogenism; dyslipidemia; glucose tolerance; type 2 diabetes; obesity; real-world evidence; artificial intelligence; preventive cardiology; clinical epidemiology.Abstract
Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine disorder with consequences extending beyond ovulatory function and androgen excess. Metabolic syndrome, impaired glucose tolerance, type 2 diabetes, dyslipidemia, hypertension, and cardiovascular morbidity are important dimensions of long-term care. Objective: To critically integrate evidence linking PCOS to metabolic syndrome and cardiovascular risk, distinguish established associations from unresolved causal pathways, and assess opportunities for real-world evidence and artificial intelligence in prevention.
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References
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