SJÖGREN’S SYNDROME
Keywords:
Sjögren’s syndrome, xerostomia, xerophthalmia, rheumatoid arthritis, systemic lupus erythematosus, lymphocytic infiltration, autoimmune damage, apoptotic products, perforin mechanisms, pSS (primary Sjögren’s syndrome).Abstract
Sjögren’s syndrome is a systemic autoimmune disease that affects connective tissues, primarily involving the exocrine glands—mainly the salivary and lacrimal glands—in the pathological process and progresses chronically. As a result of this process, dryness of the mouth (xerostomia) and dryness of the eyes (xerophthalmia) are observed. The disease can occur independently in its primary form or develop as a secondary form together with other autoimmune diseases such as rheumatoid arthritis or systemic lupus erythematosus. This article provides a scientific analysis of the pathogenetic mechanisms, clinical features, diagnostic criteria, and preventive measures of Sjögren’s syndrome. The results of the study emphasize the scientific and practical significance of early detection and effective management of the disease to promote a healthy lifestyle among the population.
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