EFFECT OF GULZOR BALM ON THE IMMUNE RESPONSE IN IRRADIATED ANIMALS WITH DIFFERENT ACETYLATION TYPES
Abstract
Recent advances in clinical sciences, particularly immunology, indicate that the pathogenesis of many diseases is, to varying degrees, associated with immune system dysfunction. Despite significant progress in the development of synthetic drugs, there remains a strong interest in plant-based remedies and their active components with immunotropic properties, especially for the treatment of chronic and long-term illnesses. Herbal immunomodulators serve as alternative therapeutic agents for various diseases, particularly in cases of weakened immune responses or selective immunosuppression, such as autoimmune syndromes.
Downloads
References
1. Irradiation at a dose of 5 Gy in slow acetylator animals causes severe immune dysfunction, reducing their thymus-dependent response to sheep erythrocytes by 7.7-fold.
2. A single administration of Gulzor Balm (0.25 mL/kg) to irradiated SA animals significantly increases antibody formation in the spleen by 4.5-fold.
3. X-ray irradiation at 5 Gy reduces the number of antibody-forming cells in the spleen of fast acetylator animals 5.6-fold.
4. Administration of Gulzor Balm to irradiated FA animals significantly increases the number of antibody-forming cells in the spleen 4.9-fold compared to irradiated controls.
5. The herbal preparation Gulzor Balm effectively corrects radiation-induced secondary immunodeficiency in mice, depending on the acetylation phenotype.
