STRUCTURAL AND FUNCTIONAL CHANGES IN LYMPHOID ORGANS AND PERIPHERAL BLOOD UNDER THE INFLUENCE OF HERBICIDES
Keywords:
herbicides, lymphoid organs, peripheral blood, immune system, hematopoietic system, lymphocytes, leukocytes, hematotoxicity, immunotoxicity, morphologicalAbstract
Herbicides are widely used in modern agriculture to control weeds and improve crop productivity. However, their excessive, prolonged, or improper use may cause adverse effects on living organisms, particularly on the immune and hematopoietic systems. Lymphoid organs, including the spleen, thymus, and lymph nodes, play a crucial role in immune defense, while peripheral blood reflects the functional state of the hematopoietic and immune systems.
Downloads
References
1. Sengupta, A., Manna, K., Datta, S., Das, U., Biswas, S., Chakrabarti, N., & Dey, S. (2017). Herbicide exposure induces apoptosis, inflammation, immune modulation and suppression of cell survival mechanism in murine model. RSC Advanc es, 7, 13957– 13970. https://doi.org/10.1039/C6RA27883C
2. Chen, J., Su, Y., Lin, F., Iqbal, M., Mehmood, K., Zhang, H., & Shi, D. (2021). Effect of paraquat on cytotoxicity involved in oxidative stress and inflammatory reaction: A review of mechanisms and ecological implications. Ecotoxicology and Environmental Safety, 224, 112711. https://doi.org/10.1016/j.ecoenv.2021.112711
3. Paraquat induced oxidative stress, DNA damage, and cytotoxicity in lymphocytes. (2022). Heliyon. https://doi.org/10.1016/j.heliyon.2022.e09895
4. Chen, X. P., et al. (2021). ADME/T-based strategies for paraquat detoxification: Transporters and enzymes. Environmental Pollution.
