PROGNOSTIC SIGNIFICANCE OF MYH7 G1816A GENOTYPES IN THE DEVELOPMENT AND CLINICAL COURSE OF CHRONIC HEART FAILURE

Authors

  • M. Kadirova
  • Kh. Musashaykhov
  • A. Aripov
  • T. Boboev

Abstract

Chronic heart failure (CHF) is one of the severe complications of ischemic heart  disease (IHD), in the development of which myocardial contractile function and  structural changes in the cardiac muscle play an important role [1–2]. The MYH7 
gene, which encodes the β-myosin heavy chain, one of the major proteins of  myocardial sarcomeres, plays an important role in these processes [3–4]. 

Downloads

Download data is not yet available.

References

1. McDonagh T.A., Metra M., Adamo M., et al. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. European Heart Journal. 2021;42(36):3599–3726.

2. McDonagh T.A., Metra M., Adamo M., et al. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. European Journal of Heart Failure. 2022;24(1):4–131.

3. Ommen S.R., Mital S., Burke M.A., et al. 2024 AHA/ACC/AMSSM/HRS/PACES/SCMR Guideline for the Management of Cardiomyopathy. Journal of the American College of Cardiology. 2024.

4. Lopes L.R., Ho C.Y., Elliott P.M. Genetics of hypertrophic cardiomyopathy: established and emerging implications for clinical practice. European Heart Journal. 2024.

5. Naderi N., Mohsen-Pour N., Nilipour Y., et al. A novel heterozygous missense MYH7 mutation potentially causes an autosomal dominant form of myosin storage myopathy with dilated cardiomyopathy. BMC Cardiovascular Disorders. 2023; 23:487.

Downloads

Published

2026-10-06

How to Cite

PROGNOSTIC SIGNIFICANCE OF MYH7 G1816A GENOTYPES IN THE DEVELOPMENT AND CLINICAL COURSE OF CHRONIC HEART FAILURE . (2026). INTERNATIONAL CONFERENCE ON ADVANCE SCIENCE AND TECHNOLOGY, 3(5), 77-78. https://universalconference.us/index.php/icast/article/view/7834