COMPARATIVE ASSESSMENT OF THE FREQUENCY OF CLINICAL MANIFESTATIONS IN PATIENTS WITH IMMUNE THROMBOCYTOPENIA
- 1. Termez Branch of the Tashkent Medical Academy Tashkent Medical Academy
Description
Objective: To analyze and compare the frequency of clinical manifestations in patients with immune thrombocytopenia depending on the severity of the disease.
Materials and methods: The study included 91 patients diagnosed with ITP in medical institutions of the Surkhandarya region from 2020 to 2024. Methods included clinical, laboratory, morphological, and statistical studies.
Results: Manifestations of hemorrhagic syndrome were observed in almost all patients with ITP, characterized by both skin and mucosal phenomena in the form of bruises and petechiae, as well as bleeding ranging from nasal to internal and renal variants. The severity and duration of the hemorrhagic syndrome corresponded to the severity of thrombocytopenia, being more pronounced in moderate and severe forms.
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References
- 1. D.S. Matkarimova, D.E. Juraeva, M.I. Nabiyeva. General overview and state of the problem of immune thrombocytopenia prevalence. // Journal of Humanities and Natural Sciences. No5 (11), 2023.
- 2. Bussel J. et al. Immune thrombocytopenia //Expert review of hematology. - 2021. - Vol. 14. - No. 11. - P. 1013-1025.
- 3. Dai F. et al. Clinical features of secondary immune thrombocytopenia associated with primary Sjögren's syndrome //Frontiers in Medicine. - 2020. - Vol. 7. - P. 138.