Published March 24, 2025 | Version v1
Conference paper Open

SOCIAL BURDEN AND GENETICS OF PELVIC ORGAN PROLAPSE

  • 1. Bukhara Medical University named after Abu Ali Ibn Sina.

Description

Pelvic organ prolapse (POP) is a common disease affecting women. Despite the high prevalence of this disease very little is known about its etiology and pathogenesis. We speculated that NAT2, GST T1 and GST M1 polymorphisms might be a predisposing factor in the development of POP. Objective: To determine the correlation between NAT2, GST T1 and GST M polymorphisms and POP.

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References

  • 1. Ward R.M., Velez Edwards D.R., Edwards T., Giri A., Jerome R.N., Wu J.M. Genetic epidemiology of pelvic organ prolapse: a systematic review // Am. J. Obstet. Gynecol. 2014. Vol. 211, N 4. P. 326-335.
  • 2. Campeau L., Gorbachinsky I., Badlani G.H., Andersson K.E. Pelvic floor disorders: linking genetic risk factors to biochemical changes // BJU Int. 2019. Vol. 108, N 8. P. 1240-1247.
  • 3. Weintraub A.Y., Glinter H., Marcus-Braun N. Narrative review of the epidemiology, diagnosis and pathophysiology of pelvic organ prolapse // Int. Braz. J. Urol. 2020. Vol. 46, N 1. P. 5-14.